Neurostimulation for Drug-Resistant Epilepsy

Neurostimulation for drug-resistant epilepsy.

PURPOSE OF REVIEW The purpose of this review is to provide an evidence-based update on the neurostimulation options available for patients with drug-resistant epilepsy in the United States and in European countries. RECENT FINDINGS The field of neurostimulation for epilepsy has grown dramatically since 1997, when vagus nerve stimulation became the first device to be approved for epilepsy by t...

Neurostimulation as a Putative Method for Treatment of Drug-Resistant Epilepsy in Patient and Animal Models of Epilepsy

A patient with epilepsy was shown to have neurobiological, psychological, cognitive, and social issues as a result of recurring seizures, which is regarded to be a chronic brain disease.However, despite numerous drug treatments, approximately, 30–40% of all patients are resistant to antiepileptic drugs. Therefore, newer therapeutic modalities are introduced into clinical practice in which invol...

Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy

Epilepsy, Consciousness and Neurostimulation

Consciousness is often disrupted in epilepsy. This may involve altered responsiveness or changes in awareness of self and subjective experiences. Subcortical arousal systems and paralimbic fronto-parietal association cortices are thought to underpin current concepts of consciousness. The Network Inhibition Hypothesis proposes a common neuroanatomical substrate for impaired consciousness during ...

Surgery for drug-resistant focal epilepsy

During the colloquium on drug-resistant epilepsy (DRE) at National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore on August 16-18, 2013, a number of presentations were made on the surgically remediable lesional epilepsy syndromes, presurgical evaluation, surgical techniques, neuropathology of drug resistance focal epilepsy and surgical outcome. This pictorial essay with the i...